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. The ability to simulate denatured-state ensembles is important for a range of applications including protein design (25,26)
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. We find that pressure does not increase the tendency of CPM-PLCβ toward the fluorescence emission properties of the activated, Gβγ-bound form (Fig
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. Differential association of the pleckstrin homology domains of phospholipases C-β1, C-β2 and C-Δ1 with lipid bilayers and the βγ subunits of heterotrimeric G-proteins
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. The crossing-over of the complex and free buildup curves at ~6 ns (Fig
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., 60%) concentrations of Gβγ on lipid membrane and at supersaturating concentrations of Gβγ are shown in Fig
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