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. "As soon as you're afraid to walk away, you lose leverage," he says
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. "--Vanessa Enoch, president, National Black MBA Association, Cincinnati chapter
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. "Congressmen would call me screaming and say, 'I thought you liked me?'" said Paul Erikson, a longtime conservative political activist who headed the PAC
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. , 1989), and the enzyme concentration-dependence observed in the process suggests that the nucleotide affects the dimer (active form)/ monomer (inactive form) equilibrium of GR
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. The influence of high hydrostatic pressure on structure, function and assembly of proteins and protein complexes
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. To our knowledge, this is the first demonstration of N-glycans affecting protein stability to such a huge extent, except for a report on a fucosylated peptide PMP-C (Pars interecrebralis major peptide C, a 36-residue peptide)
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. , folded, unfolded), the use of this signal to measure protein stability often gives rise to difficulties
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. The spectrum of the slice through the nucleus hence contained cytoplasmic signal
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. CONCLUSIONSThe wettability assessment of Sn-2
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. It was shown in a seminal article by Semisotnov and co-workers that a blue shifted ANS fluorescence spectrum and a strongly increased quantum yield is diagnostic of binding to a molten-globule-like state with exposed hydrophobic patches (Semisotnov et al
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. We attributed this unfolding to cold denaturation of the S-S linked dimer (Gursky and Atkinson, 1996b), yet other studies suggested the importance of the oligomer dissociation (Osborne et al
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. Interestingly, a closer scrutiny of the insulin aggregates obtained after 1-min incubation at 60°C indicates that clusters of swollen insulin particles tend to align within the immediate vicinity of the early fibers (Fig
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. 7 nm), and their surface appears to be structured with 6-8 subcords aligned in parallel, which are likely to be protofilaments of an individual height of ~2
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. Influence of helical junction geometry on docking efficiencyWe obtained FRET efficiency histograms for three ribozyme constructs with different helical junction geometries (natural 4WJ as well as corresponding 2WJ and 3WJ constructs; Fig
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. In other words, they might substitute relatively costly analgesic drugs, including various opiates, that are not subject to PP for those that are
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. Although the intent of the sentencing laws was not racist, their impact has been so racially skewed that it's not hard to see how people might get that impression
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. Other pain drugs accounted for another 10 percent of drug costs
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. In his address, Petri put his finger on the central dilemma the industry must overcome if it is to thrive in the 21st century: how to shift away from the long-standing perception of community pharmacists as "druggists" and create a business-model built around a deeper understanding of the real value pharmacists can bring to patient care
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. "We can coordinate benefits for people," he said
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. It's too important a time to put proprietary issues ahead of this fundamental challenge," he said
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. * As many as one-half of all American women will experience an unplanned pregnancy in their lifetime Confounding matters more is the fact that in 2004, voters listed moral values as the most important issue in the election at 22 percent, ahead of the economy/ jobs (20 percent), terrorism (19 percent) and health care (8 percent)
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. When your opponent's point level reaches zero, you win
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. The direct-to-me-side crosswind limit is 30 knots
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. Such violations include the certainty, possibility, and isolation effects
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. Probabilistic theories combine outcome values and probabilities in the long run, but not in the short run (Keren & Wagenaar, 1987; Lopes, 1983)
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- "Even if this were a gray area," says McGrath, "the implication that [our accounting for the reimbursement] is misleading is not true, because of the fact that it's disclosed in half a dozen places in the financial statement
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