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"[Paying late] is not an advisable way of improving cash flow," Weiss warns
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. Previous studies have indicated that the zinc ion is essential for the stabilization of the active site conformation as well as the protein structure (18,22-24)
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. The Mn^sup 2+^ and Ca^sup 2+^ concentrations used were 5 mM in all the experiments unless specified otherwise
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. In addition, a 10-Å distance-based cutoff was applied between all nonbonded atoms
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. Funnels, pathways, and the energy landscape of protein folding: a synthesis
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. Further, we modeled the structure of EI^sup sc^, by using the structures of the N-terminal domain of EI from E
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. Furthermore, trypsin digestion was reduced in the presence of PEP (either alone or with Mg^sup 2+^), but not in the presence of Mg^sup 2+^ alone
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. 2 shows that the MSDs for the two enzyme samples are identical, within experimental error, over the whole temperature range measured (20-285 K)
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. Decreased free rotation of the quenching cyanide groups will result in increased quantum yield
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. Using CPM-PLCβ as a readout of possible conformational changes corresponding to Gβγ activation, we monitored CPM-PLCβ fluorescence under pressure and compared it directly to using CPM-PLCβ with supersaturating levels of Gβγ-subunits
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. Furthermore, the amplitude of the light-scattering changes in apoA-1:DMPC complexes is significantly smaller than that in apoA-2 complexes, suggesting that apoA-1 inhibits disk fusion more effectively than apoA-2
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. This, as well as visualization of early unstructured aggregates, are the particularly advantageous features of AFM in studies on amyloidogenesis
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. Calculation of the absolute molecular entropy would require a complete translational and rotational sampling
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. --Pharmaceutical and Chemical SciencesUniversity of Southern California School of Pharmacy M
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- Even in Carter's long history of post-presidential grandstanding, this book sets fresh standards of irresponsibility
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. Indeed, for all 23 sequences in the EV limit we find that the absolute contact orders are independent of sequence
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. These actinomycetes are the origin of approximately two-thirds of all natural antibiotics currently produced by the pharmaceutical industry
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. Hence, the ThT assay requires a change in environment to neutral pH before fluorescence measurements
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. Linked folding and anion binding of the bacillus subtilis ribonuclease P protein
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