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The church, however, turned down the deal after "sentimentality ruled the day," said copastor Art McClellan
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. Structural rearrangements then take place at the dimer interface (and presumably also in other domains of each subunit), leading to a final, compact dimer structure
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. 02 (Perkin-Elmer) with a γ factor of 2
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. , folded, unfolded), the use of this signal to measure protein stability often gives rise to difficulties
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. laevis oocyte arrested in prophase I
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. We conclude that stabilization, and corresponding effects on the MSDs of HuBChE, by solvent/buffer and by the covalently bound inhibitor involve two different mechanisms
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. The remaining residues (see Table 1) show a weak decrease in exchange rate upon change in temperature (f [asymptotically =] 0
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. For nonionic interactions, the dominant pressure effect resides in void volumes between the protein and the membrane surface
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. Formation and metabolism of pre-β-migrating, lipid-poor apolipoprotein A-I
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. The features can be classified as: parallel tubular fibers, twisted ribbonlike structures, rod bundles, and ropelike textures
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. The consequent mutual but general attraction of the helices for each other permits the final diffusive search for the native state to take place in a two-dimensional space, rather than the full five-dimensional search configuration space of all the diffusive degrees of freedom available to the protein once the secondary structure has formed
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. Funnels, pathways and the energy landscape of protein folding
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. DISCUSSIONComparison of spFRET histograms and ensemble trFRET measurementsOur spFRET results for the wild-type ribozymes show the presence of extended (undocked) and docked conformations, with relative populations that are strongly dependent on the Mg^sup 2+^ concentration
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.6, the dimers may further aggregate to form an octamer, a structure observed predominantly at subambient temperatures (27,28)
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