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. Lectin purification on affinity columns containing reductively aminated disaccharides
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. Instead, they are soft ellipsoids that show large correlated fluctuations about mean values for R^sub g^ and δ
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. The functional form for P(x) in the EV limit has been derived by des Cloizeaux (41) as an interpolation between the predicted results for P(x) for large (87-110) and small x (111)
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. Phase transition behavior of the isolated polymer chain
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. Statins are 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors with potent antiinflammatory effects, largely due to their ability to inhibit the prenylation of Rho GTPases, including Rac-1 and RhoA
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. Comparison of the viscous behavior with predictions from the Krieger-Dougherty equation indicates the hydrodynamic size of the protein decreases with increasing concentration, resulting in a slower approach to the glass transition than a hard sphere system
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. 4, Li+ demonstrates unique behavior in this set of monocations
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. Interestingly, the midpoint and shape of the high-temperature DSC peak do not significantly change in the first and consecutive scans (curves 1-4 in Fig
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. Importantly, our studies of DMPC disks with apoA-1 (unpublished data) and apoC-1 (Mehta et al
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. Furthermore, the amplitude of the light-scattering changes in apoA-1:DMPC complexes is significantly smaller than that in apoA-2 complexes, suggesting that apoA-1 inhibits disk fusion more effectively than apoA-2
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. Taken together, our DSC, CD, light-scattering, and EM data clearly show that apoA-1:DMPC disks undergo heat denaturation at higher temperatures and are less prone to fusion than similar disks with apoA-2
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. The microscope was coupled to an AS-12 E-scanner (13-µm) and an Extender Electronics Module EX-II (Digital Instruments, Santa Barbara, CA), which allows acquisition of phase images
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. For the WT ribozymes, docked fractions (F) were calculated as a ratio of docked/undocked areas (A) as, F = A^sup docked^/(A^sup docked^ + A^sup undocked^)(Deniz et al
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. Success rates for ACI range from 60% to 90% depending on site and location of the cartilage defect
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. Estimating the impact of RP on expenditure (price x quantity) is more difficult because there are more potential confounders in this case than if we were estimating the impact of RP on price alone
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. --Pharmaceutical Sciences Toxicology* CONNECTICUTUniversity of Connecticut School of Pharmacy Ph
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. Additionally, the z-test indicated that the magnitude of the correlation coefficients between the SLSI and the PCS-12 did not vary significantly across genders or the three respective class years
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.On monetary policy issues, the report said the policy actionstaken so far ''were welcomed,'' but it ''was emphasized thatadditional steps will likely be needed
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. you'll have to focus on a single, specific muscle group and exercise that muscle group to exhaustion
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. Addition of 7 M GdnHCl completely abolished the CD signal at 222 nm, indicating extensive or complete unfolding of GR
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. Similarly, only 13 out of 53 hydrophobic interactions are intrasubunit in nature
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. The emission fluorescence spectrum of EI^sup sc^, by excitation at either 280 or 295 nm
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. Reconstitution studies using the helical and carboxyl-terminal domains of enzyme I of the phosphoenolpyruvate: sugar phosphotransferase system
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. Although PPA exhibits a strong aggregation for the thermal unfolded state, we do not observe any dependence of the magnitude of the blue shift on the heating rate
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. Organization and dynamics of tryptophan residues in erythroid spectrin: novel structural features of denatured spectrin revealed by the wavelength-selective fluorescence approach
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. Picosecond studies of the fluorescence probe molecule 8-anilino-l-naphthalenesulfonic acid
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. It is a homodimeric peptide formed via a disulfide bridge between two cysteine residues located at position 19 of the two 21-residue-long peptide strands
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.5 nm, and appears to consist of joined segments ~153 ± 8 nm long
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. As in the case of the Φ-value analysis, this experiment is also usually interpreted as giving information about the transition state (Oliveberg et al
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. Very recently, the role of nonnative interactions in stabilizing an on-pathway intermediate, together with a diffusion-collision kinetic route, has been experimentally verified in the case of the immunity protein Im7 (Capaldi et al
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