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The amide I' region of native ACYI was dominated by bands from the α-helix (1651 cm^sup -1^), α-helix and/or 3 m helix (1660 cm^sup -1^), β-sheet (1629, 1637, and 1682 cm^sup -1^), β-turn (1668 and 1674 cm^sup -1^), and random coil (1644 cm^sup -1^)
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For comparison, the δ values calculated from native structures are also shown as open circles
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At any of the explored pH, the percentages of β-hairpin (at 1693 cm^sup -1^) turns/loops/(0, π) β-sheet (at 1679 cm^sup -1^) and antiparallel β-sheet (at 1633 cm^sup -1^) remained essentially unaltered
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When we examined BAL fluid from COPD patients, we found increased numbers of apoptotic cells and decreased numbers of apoptotic cell ingestions, which is consistent with an efferocytosis defect (W
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Before comparing the behavior of individual proteins it is convenient to divide the group into two classes: one (β-gal, α-amylase, and ALD), which binds ANS essentially only in the frozen state, and the rest, which bind a fair amount of ANS also in liquid solution (4,5,28)
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Consequently, MR spectra obtained with sufficient SNR from the nucleus can be expected to reflect both the transport into the nucleus and the DNA binding of the drug
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The dimeric SEF2-1mp peptide binds within the interior of the eight-shaped CaM dimer via multiple binding alternatives
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1 as measured by Grönwall (41) is plotted in Fig
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PLCβ does not have these modifications and is aqueous soluble; however, it binds strongly to membrane surfaces with little specifically (Runnels et al
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Repetitive T-jumps with DMPC complexes containing apoA-1, apoC-1, or apoA-2 show that the protein unfolding in the first jump is slower than that in consecutive jumps (Fig
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Yet, this is precisely the insoluble, uncrystallizable character of amyloids that severely limits the number of applicable structure-determining methods, such as nuclear magnetic resonance, or x-ray diffraction
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Aggregation of bovine insulin probed by DSC/PPC calorimetry and FTIR spectroscopy
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There are, of course, many caveats attached to such a general calculation
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4), the entropy of most of the structural elements involved in the gp120/CD4 interface starts to level off after 4 ns as a result of their smaller number of atoms
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The presence of a quasi-docked conformation potentially complicates the interpretation of FRET data for the hairpin ribozyme
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126 -2,895 23,228OpiatesAverage monthly effect 492 <
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