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. The form factor p(q) or its close counterpart, the Kratky prolile (64), q^sup 2^p(q), provides average structural information across a range of wavelengths
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. Furthermore, studies with solubilizing agents such as detergents, reversed micelles, or nondetergent sulfobetaines (NDSB) proved that aggregation, which typically occurs during thermal unfolding in pure buffers, is strongly suppressed when such agents are added to the solution (29,32)
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. Using CPM-PLCβ as a readout of possible conformational changes corresponding to Gβγ activation, we monitored CPM-PLCβ fluorescence under pressure and compared it directly to using CPM-PLCβ with supersaturating levels of Gβγ-subunits
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. diameter = oil globule diameterEgg Reactivity (%)Fish egg diameter O
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. This feature is shared with Gaussian chains (39), although clear differences exist in the magnitude of and correlation between conformational fluctuations
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