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It was suggested, with the help of some computational studies, that this enhanced stability of the tetramer is mainly due to glycosylation and some stabilizing ionic interactions at the oligomeric interface (18)
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The CaM:SEF2-1mp complex is found to be highly flexible with internal motions on the picosecond, nanosecond, and microsecond timescales
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From the distribution of (τ^sup o^^sub m^) values, the shape of the diffusion tensor can be determined (30), whereas the degree of anisotropy can be gauged from the maximum and minimum (τ^sup o^^sub m^)^sub app^ values
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One proposed explanation for this behavior is that at low concentrations, a lattice type structure is formed
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1 B''), DNA coils and globules can both be recognized, and during DNA compaction the ratio between these modes changes as in a first-order phase transition
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Transmission electron microscopyFive microliter aliquots from a TTR misfolding reaction were withdrawn at different time points and were placed on a carbon coated copper grid for 2 min
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Powders made from single-domain magnetite crystals may enable the production of magnetic tapes capable of storing data at densities greater than are now possible, provided that the process can be refined so that the magnetite globules are mostly elongated along their (111) crystallo-graphic axes
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Evidence for a unique folding intermediate in the 4WJ ribozymeOur results indicate that the SL 4WJ ribozyme can fold into a compact conformation in the presence of high Mg^sup 2+^ concentrations, with arms A and B juxtaposed in a similar fashion to the docked native 4WJ ribozyme
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A second species, an American Robin, was represented only by small body feathers
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- The sound transfers and mastering are superb, likely the best these sides have ever received
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.A study by the Financial Analysis Lab at the Georgia Institute of Technology argues that insurance reimbursements for the loss of PP&E are supposed to be classified as cash flow from investing, not OCF, according to accounting rule SFAS 95, since the original purchase of such items is classified as a use of cash for investing
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. Toshiba claims the M400 can last 5 hours on its 6-cell battery
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. Asked if all these activities affected the outcome, Feeley told me simply, "I lost by only 121 votes
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. as in a helix-coil transition, then no nonnative local contacts would have to he broken upon folding
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.5 to 4 µM, and only KI was used as the quencher
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. These features (namely, the absence of tertiary structure, the lack of a sigmoidal behavior in thermal heating, solvent-exposure of hydrophobic residues, and a large amount of secondary structure) are characteristic of the so-called molten-globule species (47,48)
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. Temperature scans were performed using a constanttemperature cuvette holder connected to an external constant temperature circulator/bath (F25, Julabo, Seelbach, Germany; using a special Julabo bath fluid H10S)
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. ^sup 1^H-localized ^sup 13^C MRS of the human brain at 4 tesla
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.48 g/g) was measured by weighing shortly before closing the sample holder
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.1-10% w/w) with strong shear thinning behavior being observed with increasing shear rate (49-51) and the storage modulus, G', being larger than the loss modulus (49-53), G''
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. The compaction of giant T4 DNA proceeds as an all-or-none-type transition, and suggests the existence of only two distinct DNA states (coil and globule) and bimodality in the intermediate region (Fig
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. The most important studies on DNA-monocation binding are summarized in Table 1, which shows the activity sequences, methods used in research, and the corresponding citations in our list of references
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., the formation of the A-state and the formation of misfolded oligomeric aggregates
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., 2003a,b; Fang et al
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. The proportions decreased front 0
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.4-14 × 10^sup 3^ s^sup -1^
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. Oklahoma, Illinois, and Iowa already have laws restricting the sale of such medicines, and similar legislation is pending in 20 states across the South and Southwest
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. There is some precedent for this in the Australian state of Victoria, where officials watch for adverse effects while drugs are sold only in pharmacies and then consider whether to shift a drug to full nonprescription status
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. The report recommends measures that emphasize certain regulatory actions and the use of new technologies for safeguarding the integrity of the drug supply in the United States
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. He says that as a pharmacist he "was shocked that controls could be so loose
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. For example, chloroform causes liver cancer in female but not male mice; and though benzol and arsenic are carcinogenic in humans, they "are not so in any of the rodent species commonly used in experimental laboratories" (p
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