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. The decrease in the content of Class I Trp fluorophores suggested that the intermediate had a loose tertiary structure, which allowed the penetration of water molecules into the hydrophohic interior
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. This widelycited result provides the theoretical basis for the assertion that denatured proteins are Flory-like random coils (3,4,11,12,17,37,30)
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. Apoptosis in rheumatoid arthritis synovium
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. The sensitivity of the ANS binding method to the tertiary structure of proteins in ice should find practical utility in devising safer freeze-drying protocols of pharmaceutical proteins and testing the effectiveness of various stabilizing/ destabilizing agents employed in protein formulations
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. laevis embryos are ~1 mm in diameter, oocytes up to the 8-cell or 16-cell stages would, under optimal conditions, be observable at single-cell resolution with our (180 µm)^sup 3^ voxel size
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. In the presence of even slower internal motions it becomes progressively difficult to distinguish overall tumbling and internal motion (22,32)
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. The concentration dependence of binding of these two activators closely matches their respective concentration dependence of enzyme activation (Buck et al
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. The fastest unfolding phase in apoA-2: DMPC disks was detected during the dead-time in the denaturant-jump experiments (Ï„ Earlier CD and turbidity studies of apoC-1:DMPC disks suggested that protein unfolding is tightly coupled to disk fusion (Gursky et al
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. 1975, 1976; Fuller and Duke 1979; Marti 1973), and remains of a single prey can end up in multiple pellets (Lowe 1980)
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- A complete collection of these would already be larger than this entire set
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. And to make matters worse, according to OFHEO, when regulators began to catch on to what was happening, Raines and his team then "sought to interfere" with the OFHEO investigation by trying to get Congress to start up a separate probe of OFHEO
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. Pleiotropic effects are the multiple, often seemingly unrelated characters caused by a single gene
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. To generate ensembles that are sell-avoiding, either build-up procedures that screen for long-range hard-sphere steric overlap or Monte Carlo simulations are used
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. Interestingly enough, two peaks also appear in the unfolding of EI^sup ec^ (4)
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. However, Aguayo et al
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. It comprises three major compartments-nucleus, animal cytoplasm, and vegetal cytoplasm-which are clearly distinguished by intrinsic MRI contrast arising from the compartment-specific spin-spin relaxation times (T^sub 2^) of water, concordant with previously recorded water T^sub 2^ maps (12)
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. η^sub r,0^ increases with increasing mass fraction of protein
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. The compaction of DNA in vivo is achieved by histone proteins, which neutralize ~57% of the DNA negative charge (Morgan et al
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. DNA-cation interactions: the major and minor grooves are flexible ionophores
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.TTR is a homotetrameric transport protein circulating in the plasma and cerebrospinal fluid
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. Despite its high occurrence (78%), the salt bridge between CD4-K22(Nζ) and gp120-E429(Cδ) located at the edge of the interface of the molecular complex might be subject to fewer structural limitations than those in the center of the interface
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. The melt flow rates for the EVA 9% were greater than 0
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. We also used ANCOVA to test for a maturity stage effect in the relationship between absolute fecundity and fork length
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. Tertiary structure formation in the hairpin ribozyme monitored by fluorescence resonance energy transfer
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. Dissertation Abstracts International Section A: Humanities & Social Sciences, 62 (1-A), 332
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. Annals of the American Academy of Political & Social Science, 556, 172-185
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