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. Although gSBA was seen to demonstrate very high conformational stability, rSBA exhibits comparatively much lower firmness to resist the structural perturbation induced by the denaturant guanidinium hydrochloride
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. The number and locations of nonnative local contacts that are to be broken determine the sets of spatial contacts that are formed upon folding
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. 5), 10 mM sodium pyruvate, 1 mM MgCl^sub 2^, followed by extensive dialysis against the same buffer in the absence of MgCl^sub 2^ and pyruvate
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. It was compared to a native HuBChE sample, denoted HuBChE-H2O (0
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. MATERIALS AND METHODSSample preparationSEF2-1mp mimics the DNA- and CaM-binding region of the bHLH transcription factor SEF2-1
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. Comparison of the viscous behavior with predictions from the Krieger-Dougherty equation indicates the hydrodynamic size of the protein decreases with increasing concentration, resulting in a slower approach to the glass transition than a hard sphere system
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. Comparison of the effective radius of sterically stabilized latex particles determined by small-angle x-ray scattering and by zero shear viscosity
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. Irreversibility of the high-temperature differential scanning calorimetry (DSC) transition precluded its thermodynamic analysis
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. Then the eggs in the netwells were immersed in 100 mL of PBS in a polystyrene tray (Corning Incorporated, Corning, NY) for 5 minutes
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- Johnny Cash: The LegendMike TearsonJohnny Cash The Legend Columbia/Legacy 92802June Carter Cash Keep on the Sunny Side: Her Life In Music Columbia/Legacy 90908Johnny Cash
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.FOREX RESERVES REACH RECORD LEVELSClouse, ThomasCHINA China surpassed Japan in February to become the worlds largest holder of foreign exchange reserves, partly as a result of China's efforts to maintain the yuans exchange rate, which is fixed to a basket of currencies
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. Dielectric Behavior of Biological Molecules in Solution
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. It is on the basis of this invariance to "spatial dilatations" (39) that polymers in the EV limit are said to he rcnormalizable entities
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. Thus, the data are consistent with a motional model in which the two N-terminal and two C-terminal CaM domains in the dimeric CaM:SEF2-lmp complex undergo a small-scale wobbling motion with a half-angle of ~20° as estimated from S^sup 2^^sub s^ = 0
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.12 ml g^sup -1^) gives better agreement at higher protein concentrations (Fig
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. In this work we describe the characteristics of prefibrillar and protofibrillar assemblies of TTR and present a platform for spectroscopic characterization of these species
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. It is possible here to provide only a broad overview of the relationships involved
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.INTRODUCTIONConformational changes are central to the viral entry of human immunodeficiency virus type-1 (HIV-1), which is initiated by the mutual recognition of the HIV-1 envelope protein (Env) gp120 and the cellular receptor CD4 (Olshevsky et al
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. The histogram shows two well-resolved (non-zero) peaks, centered at E ~ 0
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.Such strategies, said Raman, have helped drive drugstore
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. The first report, issued in 2004, outlined the framework for protecting the public from counterfeit medicines
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. Abuse of a prescription drug--to get high, lose weight, or braid up muscle--can have very serious health consequences and can even be deadly
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. Given the racial overtones of the Tulia cases, it's worth noting that the officers and informants implicated in the Dallas scandal are Hispanic, like their victims
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.Mail-Order Pharmacy May Dominate DrugstoresMel DuvallThe sign on the door of Medco's Willingboro, N
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.The first piece of the puzzle is what Medco calls its Alpha system—essentially a platform for accepting and processing prescriptions before they are passed on to a pharmacy to be dispensed—which was completed in 1999
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