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. Due to the high sensitivity of tryptophan fluorescence with respect to changes in the microenvironment of the intrinsic chromophores, various properties of the unfolded state can have a distinct effect on the λ^sub max^-values
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. A surprising result is the rank order of the kinetic disk stability ΔG* ~ln τ that is evident from the timescales of the heat denaturation, apoA-1 > apoA-2 > apoC-1 (Fig
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. This mutation eliminates a tertiary hydrogen bonding interaction between G^sub 11^ (loop A) and A^sub 23^ (loop B) and is expected to destabilize the docked conformer (Rupert and Ferrc-D'Amare, 2001; Klostermeier and Millar, 2002)
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- Stein, the founder of the Carter Center's Middle East program, resigned last month to protest the book, describing it in a letter to Fox News as "replete with factual errors, copied materials not cited, superficialities, glaring omissions, and simply invented segments
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. Sequence-specific conformational preferences are restricted to local length scales that span five to nine residues
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. The FDA added six more months when Schering-Plough agreed to conduct pediatric trials of the drug
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