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. The key to the mechanism of Darwinian evolution is natural selection
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. Conversely, the contact density maps for the folded versions of different sequences reflect differences in native-state topologies
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. Previous work by us and others have employed protein engineering and cysteine labeling to attach specific probes to proteins to record conformational changes (Hammarström et al
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. Some useful characteristics of DCVJ make this a very attractive complement and alternative to ThT for amyloid and aggregation studies
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. The bottle was then placed in a homemade optical pressure cell based on the design of Paladini and Weber (1981)
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. These mature HDL, which are further remodeled by plasma enzymes, form distinct subclasses differing in size, composition and metabolic properties (reviewed by Rye and Barter, 2004)
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. According to the polymeric paradigm (Fändrich and Dobson, 2002) of amyloidogenesis and the therein-implicated importance of backbone interactions, the more the native structure becomes distorted (and the protein backbone becomes exposed), the higher the chance that the protein steps onto the amyloidogenic pathway
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. The rate determining step is not the rapid formation of local secondary structure, nor the diffusion of subdomains per se, but the organization of large pieces of secondary structure into the same topological configuration as the native state, which thereafter is able to form rapidly
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. Pseudopercis semifasciata larvae were distinguished from other larvae by the modal number of myomeres (between 36 and 38), their elongated body, the size of their gut, and by osteological features of the neuro- and branchiocranium
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. Markham Endowment Award; and the 1998 Bill Wick Marine Fisheries Award
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. Manuscript submitted 4 April 2003 to Scientific Editor's Office
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. For histogram simulations of the SL 4WJ at 10 mM Mg^sup 2+^, the state of the ribozyme system was allowed to stochastically switch between the extended undocked and quasi-docked states according to the assumed forward and reverse rate constants (see Fig
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. Financial support was received by the Engineering and Physical Sciences Research Council, UK, as part of its core grant to the IRC in Biomedical Materials
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- Air Force, Cash signed with Sam Phillips, the legendary producer of Sun Records in Memphis who also mentored the fledgling career of Elvis Presley
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.* In the shadow of New York's Empire State Building, the quaint Episcopal Church of the Transfiguration razed its parish house and sold its air rights for a 55-story luxury condo building that will net about $7 million for the congregation
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.379 Mathnasium Learning2002/2003AllCenters404 Oxford Learning1984/1989AllCenters Inc
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. Some additional explanation is here requisite which I cannot give
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