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. This helix-loop-helix motif folded against the ban-el, covering a hydrophobic patch (which includes Tip^sup 461^): the motif was linked to the barrel by two salt bridges, namely, Arg^sup 537^-Asp^sup 467^ and Arg^sup 546^-Asp^sup 459^ (Fig
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. These calreticulin/PS-rich patches distribute away from regions rich in CD47 (a newly described "don't-eat-me" signal on viable cells), (11,17,18) ultimately resulting in enhanced effrocytosis
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. Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals
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. Most probable a well-pronounced aggregation of the thermal unfolded state contributes to the burial of tryptophan residues (discussion of this subject follows in the next section)
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. The aceturate linewidth in the nucleus does not change, which we attribute to the constant lack of macromolecule binding
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. Moreover, protein unfolding and dissociation in this transition lead to thermodynamically irreversible disk fusion, as indicated by the DSC, EM, and gel electrophoresis data (Fig
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. It is worth noting that the peak centered around 1639 cm^sup -1^ at temperatures above 80°C in the difference absorption spectra (Fig
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