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These have included--to name just two examples--his letter-writing campaign in 1990 to members of the United Nations Security Council, in an effort to thwart the Bush I coalition that fought the first Gulf War against Saddam Hussein; and his 1994 trip to North Korea, where he proposed to the dying tyrant Kim Il Sung a deeply flawed nuclear-freeze deal that may well have helped Kim's son consolidate power and develop ICBMs and atomic bombs
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Protein interiors in the EV limit reveal cavities on all length scales Field theories predict that chains in the EV limit are characterized by interior cavities of all sizes, reflecting the inefficient way in which the chains fill the available volume (39)
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Given the equivalence between the EV limit and highly denatured states, our ability to simulate conformational ensembles in the EV limit, with full atomic detail, has direct bearing on the development of an accurate physical picture of conformations accessible to denatured proteins
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Furthermore, the extent of ANS binding was sharply modulated by conditions that affect the thermodynamic stability of the protein
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The same is true for DCVJ (Fig
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- Louis, Cleveland, and others, to write a candidly informative expose of what happens "back stage" in the world of talk radio
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. Overall, then, the longest-necked animals were the best-fed members of the population
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. These maps show regions where contacts are either present (strong) or absent (weak) in both the native and denatured states
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. Finally, CD31 (also known as platelet-endothelial cell adhesion molecule-l) is a fascinating molecule with dual roles, functioning as both a don't-eat-me (detachment) signal on viable leukocytes and as an eat-me facilitator on apoptotic leukocytes
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. This crossover indicates the approach of a dynamic transition which can be compared to the colloidal glass transition (5,70)
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., 1999) to CPM-PLCβ gave a volume change similar to Gβγ-subunits (Table 1), which suggests that the contacts made by this peptide reflect the same ones made by the whole Gβγ-subunit (see Discussion)
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. The AFM-samples were dried gently with a nitrogen flow and left to dry overnight before the measurements, which helps improve the quality of the AFM data
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. This result confirms that the sizable increases in E with Mg^sup 2+^ that we observe for the 2WJ (WT and SL) and SL 4WJ ribozymes are due to decreases in the interarm distances
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