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. 6), although isothermal melt done with rSBA at this protein concentration still shows a three-state unfolding profile
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. making the monomermonomer interaction less stable
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. This feature can either by related to arising tyrosine emission (often observed around 305 nm for unfolded states when energy transfer to tryptophans disappears during a structural expansion of the protein; see, for example, Schmid (20)) or to elastic scattering caused by aggregation
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. The mitochondrial DNA quantity varies with species and cell type, and for a mature X
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. The ratio of R^sup 2^ over R^sup 1^ (R^sup 2^ corrected for R^sub ex^; vide infra) at a magnetic field B gives the apparent correlation time, (τ^sup B^^sub m^)^sub app^ (Eq
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. Time-resolved fluorescence anisotropy decay of ANS was shown to be a useful tool for giving further structural and kinetic information of the oligomeric aggregates
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- The least well known of this set is, musically speaking, no great shucks
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.Gorelick's situation was similar
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. The mean residue ellipticity of the recombinant protein was similar to that of the wild-type, suggesting that there are no major structural changes between the native glycosylated and recombinant nonglycosylated proteins (Fig
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. The use of theories based on perturbations around the Θ state is only valid in the limit T [arrow right] Θ or small N
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. Study of the membrane permeability of a paramagnetic complex on single cells by NMR microscopy
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. The contact angles measured from the wetting balance test were used in the modeling to estimate the corresponding maximum wetting forces and the meniscus heights
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.Binding affinity of ANS, DCVJ, and ThT to early misfolded TTR oligomersSamples containing 1 µM total concentration of misfolded A-state TTR monomers packed into soluble oligomers harvested 2 h after misfolding initiation were used as bait for probe binding
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.To minimize possible distortional effects, the lateral size determination method was applied
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. By handing off workers' drug-benefit programs to huge automated mail-order facilities like Medco's, businesses hope to put a dent in prescription costs that have been growing at about 15% a year since 1999
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.The correlation coefficient results between the Student-Life Stress Inventory and the physical (PCS-12) and mental (MCS-12) component health related quality of life scores for the study sample are presented in Table 4
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