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This leads us to further understanding of intermediate protein structures in the unfolding process
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From the difference contact maps, we find that upon folding, specific nonnative local contacts have to be broken (weakened) to make native, nonlocal spatial contacts
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Analysis of difference contact maps suggests that to fold, the dilatation symmetry in the EV limit is broken by weakening specific nonnative local contacts
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Native proteins are surface-molten solids: application of the Lindemann criterion for the solid versus liquid state
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Rather solvent accessible tryptophan residues in the folded state (Fig
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Lyophilized BSA, β-gal from Aspergillus oryzae and yeast alcohol dehydrogenase (YADH), and crystalline suspensions of α-amylase from porcine pancreas, ALD from rabbit muscle and LDH from rabbit muscle (LDH) were purchased from Sigma-Aldrich Co
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We conclude that functional differences arising from these structural differences are either of a local nature (e
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INTRODUCTIONHigh-density lipoproteins (HDLs) are heterogeneous complexes of lipids and specific proteins (termed exchangeable apolipoproteins) that mediate cholesterol removal from peripheral tissues to the liver via the process termed reverse cholesterol transport (Fielding and Fielding, 1995)
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Despite limited accuracy in the particle size determination and limited resolution, this system facilitates observation of lipoproteins, lipid-free and lipid-poor proteins on the same gel and is widely used for lipoprotein analysis (Davidson et al
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Specifically, the pressure-induced growth of the circular insulin amyloid suggests anisotropic packing within an ambient protofilament
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4 mm BL preflexion larvae
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Systematic revision of the South American species of Pinguipedidae (Teleostei, Trachinoidei)
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We studied the effect of dissolving temperature and Isopar type (G, H, and L) on the average particle size
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ANSWERS TO QUIZ QUESTIONS:1
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For underage participants, there was no significant difference between gender on the item of having gambled in a casino with 71
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The overall trend was that, when players had control of cards, they attributed the outcomes more to their ability when they won than when they lost [ILLUSTRATION FOR FIGURE 1 OMITTED]
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. However, the order of events from Fig
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. Mol Cell 2004; 14:277-287(17) Gresham HD, Dale BM, Potter JW, et al
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. The measured weights were taken as their dry weights (h = 0 g water/g dry powder, denoted by g/g in the following)
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. Figure 8 exhibits the dependency of wetting force and meniscus height on the perimeter (P) of the substrate
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. Fluorescence anisotropy data from Bis-ANS bound to the different unfolded and aggregated states showed modest anisotropy values (compared to when bound to the thyroxine binding site in the native TTR tetramer), revealing that Bis-ANS docs not penetrate the protein but is more loosely associated to the protein surface (data not shown)
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.The interpretation of nonclassical Φ-values outlined here is closely-related to a recent suggestion arising from some simple lattice Go-type simulations (Ozkan et al
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.The objectives of the research [14] reported in this paper are to produce toners using binders with high flexibility (low T^sub g^ and high elongation) and to evaluate the properties of fabrics printed with these toners
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.Figure 4 shows a typical particle size distribution for these experiments
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.The average burst duration for the SL 4WJ at 10mM Mg^sup 2+^ was estimated from two-channel data acquired with time bins of 50 µs, by averaging the burst durations within each 500-µs rebinned point lying above a threshold of 40
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.Although trFRET and diffusion spFRET provide a consistent view of the overall tertiary folding of the hairpin ribozyme, spFRET is more direct and can provide additional information
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