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When out of control--which was much too often--Cash wrecked property, nearly killed himself in a borrowed car, and was arrested seven times
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. The results are discussed in terms of the mechanism of GR folding and dimerization
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. Collectively, we have worked with blind cave organisms for more than eighteen years, and one of us (Luis Espinasa) was working with blind cave fish in Jeffery's laboratory shortly after the publication of the momentous work on lens transplants
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. Catabolism of intracellular N-terminal acetylated proteins: involvement of acylpeptide hydrolase and acylase
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. For comparison, the δ values calculated from native structures are also shown as open circles
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. (15) recorded an MR spectrum from a (220 µm)^sup 3^ voxel within an A
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. , in photosynthesis) to folding processes that can take minutes or longer (1)
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. The sliding process is likely to occur on a nanosecond timescale, although CaM:SEF2-lmp interactions may slow down this process in some instances
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. Clear evidence of the lack of a binding-compaction correlation was seen in studies on DNA compaction by enantiomeric dications (Zinchenko et al
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. The large-amplitude relocalization of the V3 loop of gp120 upon binding is, however, free from any substantial entropic cost
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- Bill Hilton, Vice President, Patient Financial Services, Carilion Health Systems, a six hospital system located in western Virginia
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. The group was also one of 10 members of the 21st Century Energy Project, an Enron-funded group set up by former Republican National Committee chair Ed Gillespie
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. A note on the molar absorptivity of reduced Ellman's reagent, 3-carboxylato-4-nitrothiophenolate
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. The width of the olfactory pit in blind fish increases on average by 13 percent, thus enlarging the surface of the olfactory epithelium, where the chemical receptors are lodged [see illustration on opposite page]
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. To assay conformational preferences of highly denatured proteins, we quantify a variety of properties for EV-limit ensembles of 23 two-state proteins
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. The idea is that in a perfect solvent, chain-solvent interactions exactly counterbalance all non-EV intrachain interactions (38)
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. Our ability to simulate mimics of denatured-state ensembles will allow us to ask precise questions about the role of the denatured state in the types of applications outlined above
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. In conclusion, our approach suggests that thermodynamical analysis might reveal subtle contormational changes in otherwise similar folds
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. Steady-state and quenching experiments were acquired at 298 K
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. At physiological temperatures, atomic mean-square displacements (MSDs) measured by IENS reflect sampling of conformational substates (entropy) as well as vibrational amplitudes
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. For prolate ellipsoids of this aspect ratio, the maximum packing fraction is ~0
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. The Trp fluorescence of acid unfolded TTR peaks at 352 nm (data not shown) compared to 340 nm in the native protein, indicating unfolding
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.4 µM for ANS, and 6
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. Structures of apolipoprotein A-II and a lipid-surrogate complex provide insights into apolipoprotein-lipid interactions
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.3 61EH-04/9965[degrees]14'Pseudopercis1449
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